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KMID : 0388219950020020126
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Journal of the Korean Rheumatism Association
1995 Volume.2 No. 2 p.126 ~ p.132
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The Effect of Bucillamine of Trace Element Levels of Hair in Patients with Rheumatoid Arthritis
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전재범
유대현/김동욱/김순길/김태환/김승영/김평남/정성수/이인홍
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Abstract
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Objective :
@EN We investigated the changes of trace element levels in hair of patients with rheumatoid arthritis after bucillamine treatment.
@ES Methods :
@EN We performed inductively coupled plasma atomic emission spectrometry in determination of trace element levels in hair of patients with rheumatoid arthritis.
@ES Results : The results were as follows:
@EN 1) There was a significant increase of copper concentration, but no change in zinc level after bucillamine treatment. 2) There were no significant changes in copper and zinc concentrations between the proximal and distal portions of hair
after
long-term bucillamine treatment.
@ES Conclusion :
@EN Our results showed the significant increase of copper level and no significant change of zinc level in hair after bucillamine treatment, but, although statistically not sgnificant, copper and zinc levels were decreased on experiment with
divided
hair. So, our findings do not permit any cnoclusion on the influsence of bucillamine on trace element levels in hair. Further studies in larte samples and comparison with the effect of D-penicillamine will be necessary to clarify the association
of
trace element levels in hair of rheumatoid arthritis patients and buci9llamine treatment.
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KEYWORD
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